Detalhe da pesquisa
1.
Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective.
Cell
; 187(2): 446-463.e16, 2024 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38242087
2.
Integrative analysis of 111 reference human epigenomes.
Nature
; 518(7539): 317-30, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25693563
3.
Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1.
Proc Natl Acad Sci U S A
; 114(40): 10743-10748, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28916733
4.
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods.
Genome Res
; 23(9): 1541-53, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23804401
5.
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.
Genome Res
; 23(9): 1522-40, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23804400
6.
Conserved role of intragenic DNA methylation in regulating alternative promoters.
Nature
; 466(7303): 253-7, 2010 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20613842
7.
Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment.
Acta Neuropathol
; 129(4): 597-607, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25724300
8.
Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3.
Nat Genet
; 37(6): 645-51, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15895082
9.
Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression.
Neuro Oncol
; 26(4): 640-652, 2024 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38141254
10.
Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma.
Sci Rep
; 14(1): 6362, 2024 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493204
11.
Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors.
Nat Genet
; 32(3): 453-8, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12355068
12.
Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma.
bioRxiv
; 2023 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961484
13.
Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens.
bioRxiv
; 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37904942
14.
Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs.
Neuro Oncol
; 25(12): 2221-2236, 2023 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37436963
15.
Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer.
Nat Commun
; 13(1): 5430, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114166
16.
Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.
Neuro Oncol
; 24(11): 1898-1910, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35460557
17.
Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease.
Dev Cell
; 56(9): 1238-1252.e5, 2021 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891899
18.
Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas.
Neuro Oncol
; 23(11): 1872-1884, 2021 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33823014
19.
Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth.
Proc Natl Acad Sci U S A
; 104(26): 10974-9, 2007 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-17578925
20.
MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence.
Neuro Oncol
; 22(11): 1580-1590, 2020 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32166314